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CASE STUDY · YRI FELLOW

From curious 9th grader to 1st place science fair winner and state qualifier

Avyay built a multi-model AI pipeline predicting time-to-onset of respiratory disease from combined air pollution exposure and genetic susceptibility, using WHO Global Air Quality data with GEO gene expression datasets. He compared Kaplan-Meier, Cox Proportional Hazards, AFT, Random Survival Forests and DeepSurv with SHAP explainability for clinically actionable predictions. Higher pollution accelerated disease onset, especially in genetically susceptible individuals.

FIELDAI & Computational Biology
RESULT1st Place Science Fair and State Qualifier
VENUETwin Cities Regional Science Fairs, 2026
Avyay G.
Avyay G., YRI Fellow1ST PLACE
BEFORE THE FELLOWSHIP

A 9th grader passionate about AI and healthcare with no prior research or publication experience.

AFTER

1st place science fair winner with advanced AI research, qualified for state competition.

YRI helped me integrate air pollution data with genetic susceptibility to build AI models predicting respiratory disease risk. My research won 1st place at my science fair, something I never imagined achieving in 9th grade.
AVYAY G.
Achievement announcement
Achievement announcement
Minnesota Academy of Science state science fair promotion letter
Minnesota Academy of Science state science fair promotion letter
USMA special award for Best Use of SI Units
USMA special award for Best Use of SI Units
THE LEDGER
011st place in category at the Twin Cities Regional Science Fairs, March 2026
02Won 4 ribbons and qualified for the state science fair
03USMA Special Award for Best Use of SI Units
04Compared 5 or more survival models including Random Survival Forests and DeepSurv
05Predicted 28% faster disease onset with high pollution exposure
NEXT CASE STUDYAarush Mahajan, 3rd Place globally, Project Green Challenge 2025

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